Oh, like the Target-exclusive Oregon Trail handheld? Sheesh, I hope not.
Though I would be all over a dedicated X-wing/TIE Fighter handheld if it were handled well, with custom controls and a cool case.
I have the Oregon Trail handheld and liked it a lot (review link). I definitely think there's a future in this form factor/style as long as you target the right games (Carmen Sandiego was one that immediately came to mind). Certainly the Star Wars games and the like would easily fit that mold, although those HAVE been explored quite aggressively in various plug and plays already, albeit not in the more sophisticated form of X-Wing/Tie Fighter. Still, at least until too many of these get released, I'd definitely be down with a few more single game, "deluxe" handhelds like the Oregon Trail.