Zelda II: Adventure of Link-- Those flying skulls (called bubbles) in the palaces and take numerous hits to get rid of them. Also, the bubbles in certain stages that rise from pits. Hit one of those and you'll end up falling back into a pit.
Scrapyard Dog for the 7800. Just about every enemy including the fire hydrants and basketballs. Not to mention the jumps in the sewer level.