Press the left fire button and choose STS-101. Then press #, And get ready for a countdown. Press 1 to start main engines at about 8 seconds. (It take a few seconds to start the countdown) Once it gets to 5 seconds, Thrust by pressing the left fire button and hold it down.(follow the red line as it moves to the right). Steer the ship up down left and right. But watch your altitude, If you get too high, It will abort. You have to stop at 210k feet. NOTE: That's as far as i got because we need the 4 sub manuals or its impossible to play any farther.