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According to the internet, the difference between DNA & mRNA vaccines is that the DNA ones require an electrical device to push the "stuff" into the cell. Whereas mRNA just kinda goes in on its own. Don't quite understand how "journalists" can get paid good money citing such basic inaccuracies.
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Only thing I’ve gotten out of the info concerning this, is that the research behind the vaccine goes 15 years back in time.
The Corona Virus looks like a ball with spikes.
These spikes, attach to cells, tear open a hole, enter, insert the viral RNA onto the cell DNA and makes the cell produce corona viruses.
Then the cell explodes and releases a ton of Corona viruses which goes on to do the same.
But Moderna-labs, found out it was more efficient to inoculate (teach the immune-system) to target the attaching spikes rather than the entire corona-virus itself.
This, at least initially, became the platform for vaccines.
However they may have improved it a lot.
But I wouldn’t find it improbable that the guy leading the Moderna anti-Corona vaccine may receive a Noble price.
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Maybe.. Moderna vaccine doesn't induce CD8 T-cell memory, and therefore is not as complete as Pfizer's immune system "training". This is like security at a stadium where all nefarious patrons are stopped at the front door. And nobody, absolutely nobody gets hauled to back security office for additional questioning. And therefore the security force is not as well versed on the nature of the troublemakers.
All the tested vaccines are still providing protection 6-8 months after their first use in the early trials. Or for however long they've been on the market. But no one knows how long that will last. We just have to wait and see.
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There isn't really any exploding and tearing open of cells. It's more of an intricate lock and valve mechanism on a molecular scale. The Spike and ACE-2 receptors interlock and unfold. A zipper-like interface with handles, hinges, and fingers is formed between the virus and outer cell membrane. And the virus unfolds its capsid after membranes merge. It's a very specific and slow process. Rather elegant instead of just BOOOM!!
The cells don't really explode. As their insides fill up with virus, their own machinery can't maintain any cohesion, let alone the cells outer membrane. It kinda dissolves and falls apart.
TRIVIA: the pressure inside some capsids is 80psi or more.
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