Ok, I understand now what are you referring to. Surely, it would speedup FP calculations and such, but in fact FP calculations are rarely used. I guess that all the gain would be wasted on communications with the cartridge and its coprocessor. You know, the calculations even the BASIC interpreter does are mostly ordinary integer stuff, most of the speed gain you can do with an accelerator comes from the fact that every CPU instruction is executed faster - not from the fact that just FP calculations are faster.
I can't imagine how it could configure the system f.e. to use the native mode interrupts, in the other way than replacing the XL OS with something loaded into the RAM below the OS. This is "replacing the OS" I mentioned above and it is way better done by replacing the ROM. There are already some 32-in-one OS-es, so what is the problem with adding one more, this time really necessary?
Yes. The high RAM (past the $FFFF) is clocked at 7 MHz currently, maybe 14 MHz in the near future.