I just upgraded from my 3DS (small) to a New 3DS XL. Loving it with the exception of one thing. The location of the power button!
When playing RPG's during cutscenes / heavy text sections, I'll relax and hold my system one handed, using my ring finger to prop it up at the bottom, and my thumb tapping A to continue. Where I'm used to my ring finger going is now the position of the power button.
Just gave Pokemon Omega Ruby a good play for 4.5 hours, and accidentally hit the power button.
I never saved. Not once.